Skin sensitization test
For the standard 10 compounds of the h-CLAT (P1 – N10), similar results to those in model cells (LLNA) can be obtained. Time and cost can be drastically reduced because our method is free from the time-consuming procedures and confirmation required in the h-CLAT.
Comparison study with the h-CLAT.
Our method showed consistent responses to compounds to which inconsistent responses were observed between CD86 and CD54 in the h-CLAT, and our results were similar to those in LLNA.
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